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Spinsplit proudly presents white papers and journal papers where our products were utilised for the scientific experiments.

Our Whitepapers

A comprehensive reference to: Electrostatic fiber formation

An introduction to: Oriented fiber formation

Nanofibers in Pharma

Balogh-Weiser, D., Molnár, A., Tóth, G. D., Koplányi, G., Szemes, J., Decsi, B., Katona, G., Salamah, M., Ender, F., Kovács, A., Berkó, S., Budai-Szűcs, M., & Balogh, G. T. (2023). Combined Nanofibrous Face Mask: Co-Formulation of Lipases and Antibiotic Agent by Electrospinning Technique. Pharmaceutics, 15(4), 1174. https://doi.org/10.3390/pharmaceutics15041174
Balogh-Weiser, D., Németh, C., Ender, F., Gyarmati, B., Szilágyi, A., & Poppe, L. (2018). Electrospun Nanofibers for Entrapment of Biomolecules. In T. Tański, P. Jarka, & W. Matysiak (Eds.), Electrospinning Method Used to Create Functional Nanocomposites Films. InTech. https://doi.org/10.5772/intechopen.76068
Balogh-Weiser, D., Poppe, L., Kenéz, B., Decsi, B., Koplányi, G., Katona, G., Gyarmati, B., Ender, F., & Balogh, G. T. (2022). Novel biomimetic nanocomposite for investigation of drug metabolism. Journal of Molecular Liquids, 368, 120781. https://doi.org/10.1016/j.molliq.2022.120781
Józó, M., Simon, N., Yi, L., Móczó, J., & Pukánszky, B. (2022). Improved Release of a Drug with Poor Water Solubility by Using Electrospun Water-Soluble Polymers as Carriers. Pharmaceutics, 14(1), 34. https://doi.org/10.3390/pharmaceutics14010034
Kazsoki, A., Palcsó, B., Alpár, A., Snoeck, R., Andrei, G., & Zelkó, R. (2022). Formulation of acyclovir (core)-dexpanthenol (sheath) nanofibrous patches for the treatment of herpes labialis. International Journal of Pharmaceutics, 611, 121354. https://doi.org/10.1016/j.ijpharm.2021.121354
Kazsoki, A., Palcsó, B., Omer, S. M., Kovacs, Z., & Zelkó, R. (2022). Formulation of Levocetirizine-Loaded Core–Shell Type Nanofibrous Orally Dissolving Webs as a Potential Alternative for Immediate Release Dosage Forms. Pharmaceutics, 14(7), 1442. https://doi.org/10.3390/pharmaceutics14071442
Kazsoki, A., Farkas, A., Balogh-Weiser, D., Mancuso, E., Sharma, P. K., Lamprou, D. A., & Zelkó, R. (2020). Novel combination of non-invasive morphological and solid-state characterisation of drug-loaded core-shell electrospun fibres. International Journal of Pharmaceutics, 587, 119706. https://doi.org/10.1016/j.ijpharm.2020.119706
Kovács, A., Kazsoki, A., Démuth, B., Szirányi, B., Madarász, J., Süvegh, K., & Zelkó, R. (2020). Influence of Aqueous Solubility-Enhancing Excipients on the Microstructural Characteristics of Furosemide-Loaded Electrospun Nanofibers. Pharmaceutics, 12(4), 385. https://doi.org/10.3390/pharmaceutics12040385
Németh, K., Kazsoki, A., Visnovitz, T., Pinke, B., Mészáros, L., Buzás, E. I., & Zelkó, R. (2022). Nanofiber formation as a promising technology for preservation and easy storage of extracellular vesicles. Scientific Reports, 12(1), 22012. https://doi.org/10.1038/s41598-022-25916-6
Palcsó, B., Kazsoki, A., Herczegh, A., Ghidán, Á., Pinke, B., Mészáros, L., & Zelkó, R. (2022). Formulation of Chlorine-Dioxide-Releasing Nanofibers for Disinfection in Humid and CO2-Rich Environment. Nanomaterials, 12(9), 1481. https://doi.org/10.3390/nano12091481
Sipos, E., Kósa, N., Kazsoki, A., Szabó, Z.-I., & Zelkó, R. (2019). Formulation and Characterization of Aceclofenac-Loaded Nanofiber Based Orally Dissolving Webs. Pharmaceutics, 11(8), 417. https://doi.org/10.3390/pharmaceutics11080417
Tóth, G. D., Kazsoki, A., Gyarmati, B., Szilágyi, A., Vasvári, G., Katona, G., Szente, L., Zelkó, R., Poppe, L., Balogh-Weiser, D., & Balogh, G. T. (2021). Nanofibrous Formulation of Cyclodextrin Stabilized Lipases for Efficient Pancreatin Replacement Therapies. Pharmaceutics, 13(7), 972. https://doi.org/10.3390/pharmaceutics13070972
Tóth, G. D., Kállai-Szabó, N., Lengyel, M., Süvegh, K., Ender, F., Katona, G., Kazsoki, A., Zelkó, R., Antal, I., Balogh, G. T., & Balogh-Weiser, D. (2023). Nanoformulation of lipase from Porcine pancreas by electrospinning as a novel alternative for enzyme-based per os therapies. Journal of Molecular Liquids, 389, 122819. https://doi.org/10.1016/j.molliq.2023.122819
Yi, L., Luo, S., Cui, L., Budai-Szűcs, M., Móczó, J., & Pukánszky, B. (2022). Processes taking place during the preparation and use of electrospun PLA fibers and their effect on controlled drug release. Journal of Thermal Analysis and Calorimetry, 147(23), 13191–13199. https://doi.org/10.1007/s10973-022-11554-7

Other nanofiber applications

Hegedus, K., Ender, F., & Plesz, B. (2022). Controlled Deposition of Perovskite Thin Layer with Electrospraying for Solar Cells. 2022 18th Biennial Baltic Electronics Conference (BEC), 1–5. https://doi.org/10.1109/BEC56180.2022.9935586
Józó, M., Várdai, R., Hegyesi, N., Móczó, J., & Pukánszky, B. (2021). Poly-ε-Caprolactone/Halloysite Nanotube Composites for Resorbable Scaffolds: Effect of Processing Technology on Homogeneity and Electrospinning. Polymers, 13(21), 3772. https://doi.org/10.3390/polym13213772
Koplányi, G., Sánta-Bell, E., Molnár, Z., Tóth, G. D., Józó, M., Szilágyi, A., Ender, F., Pukánszky, B., Vértessy, B. G., Poppe, L., & Balogh-Weiser, D. (2021). Entrapment of Phenylalanine Ammonia-Lyase in Nanofibrous Polylactic Acid Matrices by Emulsion Electrospinning. Catalysts, 11(10), 1149. https://doi.org/10.3390/catal11101149
Koplányi, G., Bell, E., Molnár, Z., Katona, G., Lajos Neumann, P., Ender, F., Balogh, G. T., Žnidaršič‐Plazl, P., Poppe, L., & Balogh‐Weiser, D. (2023). Novel Approach for the Isolation and Immobilization of a Recombinant Transaminase: Applying an Advanced Nanocomposite System. ChemBioChem, 24(7), e202200713. https://doi.org/10.1002/cbic.202200713
Pardy, T., Joemaa, R., Ender, F., Rang, T., Hegedus, K., & Balogh-Weiser, D. (2020). Polymer Nanofiber Deposition in Lab-on-a-Chip Devices By Electrospinning. 2020 17th Biennial Baltic Electronics Conference (BEC), 1–4. https://doi.org/10.1109/BEC49624.2020.9277494

Flow chemistry applications

Balogh, G. T., Decsi, B., Krammer, R., Kenéz, B., Ender, F., Hergert, T., & Balogh-Weiser, D. (2022). Effect of Binding Linkers on the Efficiency and Metabolite Profile of Biomimetic Reactions Catalyzed by Immobilized Metalloporphyrin. Metabolites, 12(12), 1269. https://doi.org/10.3390/metabo12121269
Balogh-Weiser, D., Decsi, B., Krammer, R., Dargó, G., Ender, F., Mizsei, J., Berkecz, R., Gyarmati, B., Szilágyi, A., Tőtős, R., Paizs, C., Poppe, L., & Balogh, G. T. (2020). Magnetic Nanoparticles with Dual Surface Functions—Efficient Carriers for Metalloporphyrin-Catalyzed Drug Metabolite Synthesis in Batch and Continuous-Flow Reactors. Nanomaterials, 10(12), 2329. https://doi.org/10.3390/nano10122329
Decsi, Krammer, Hegedűs, Ender, Gyarmati, Szilágyi, Tőtős, Katona, Paizs, Balogh, Poppe, & Balogh-Weiser. (2019). Liver-on-a-Chip‒Magnetic Nanoparticle Bound Synthetic Metalloporphyrin-Catalyzed Biomimetic Oxidation of a Drug in a Magnechip Reactor. Micromachines, 10(10), 668. https://doi.org/10.3390/mi10100668
Ender, F., Hegedus, K., Cseko, R., & Poppe, A. (2022). Built-in Thermal Test as a Pre-Integrated Architecture. 2022 45th International Spring Seminar on Electronics Technology (ISSE), 1–5. https://doi.org/10.1109/ISSE54558.2022.9812759
Gal, C. A., Barabás, L. E., Bartha Vári, J.-H., Moisă, M. E., Balogh-Weiser, D., Bencze, L. C., Poppe, L., Paizs, C., & Toșa, M. I. (2021). Lipase on carbon nanotubes – an active, selective, stable and easy-to-optimize nanobiocatalyst for kinetic resolutions. Reaction Chemistry & Engineering, 6(12), 2391–2399. https://doi.org/10.1039/D1RE00342A
Hamidović, M., Ender, F., & Springer, A. (2020). A Novel Enzymatic Microreactor: Towards Transforming the Pharmaceutical Industry. In A. Badnjevic, R. Škrbić, & L. Gurbeta Pokvić (Eds.), CMBEBIH 2019 (pp. 303–308). Springer International Publishing. https://doi.org/10.1007/978-3-030-17971-7_46
Hegedus, K., Hantos, G., Pardy, T., & Ender, F. (2020). In-situ Thermal Performance Monitoring of Pharma 4.0 Flow Bioreactors. 2020 26th International Workshop on Thermal Investigations of ICs and Systems (THERMINIC), 1–4. https://doi.org/10.1109/THERMINIC49743.2020.9420529
Imarah, A. O., Silva, F. M. W. G., Bataa, N., Decsi, B., Balogh-Weiser, D., & Poppe, L. (2023). Magnetically agitated continuous-flow tube reactors with aspartate ammonia-lyase immobilized on magnetic nanoparticles. Reaction Chemistry & Engineering, 8(6), 1250–1259. https://doi.org/10.1039/D2RE00507G
Palovics, P., & Rencz, M. (2018). Simulation of the magnetic nanoparticle filling procedure of microchambers. 2018 Symposium on Design, Test, Integration & Packaging of MEMS and MOEMS (DTIP), 1–5. https://doi.org/10.1109/DTIP.2018.8394192
Pálovics, P., Ender, F., & Rencz, M. (2018). Geometric optimization of microreactor chambers to increase the homogeneity of the velocity field. Journal of Micromechanics and Microengineering, 28(6), 064002. https://doi.org/10.1088/1361-6439/aab1c3
Pálovics, P., Ender, F., & Rencz, M. (2018). Towards the CFD model of flow rate dependent enzyme-substrate reactions in nanoparticle filled flow microreactors. Microelectronics Reliability, 85, 84–92. https://doi.org/10.1016/j.microrel.2018.03.035
Silva, F. M. W. G., Imarah, A. O., Takács, O., Tuba, L., & Poppe, L. (2023). Scalability of U-Shape Magnetic Nanoparticles-Based Microreactor–Lipase-Catalyzed Preparative Scale Kinetic Resolutions of Drug-like Fragments. Catalysts, 13(2), 384. https://doi.org/10.3390/catal13020384

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